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Chromosome healing in mouse embryonic stem cells

The addition of new telomeres to the ends of broken chromosomes, termed chromosome healing, has been extensively studied in unicellular organisms; however, its role in the mammalian cell response to double-strand breaks is unknown. A system for analysis of chromosome healing, which involves the inte...

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Autors principals: Sprung, Carl N., Reynolds, Gloria E., Jasin, Maria, Murnane, John P.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC21992/
https://ncbi.nlm.nih.gov/pubmed/10359789
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