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Chromosome Instability as a Result of Double-Strand Breaks near Telomeres in Mouse Embryonic Stem Cells

Telomeres are essential for protecting the ends of chromosomes and preventing chromosome fusion. Telomere loss has been proposed to play an important role in the chromosomal rearrangements associated with tumorigenesis. To determine the relationship between telomere loss and chromosome instability i...

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Bibliografische gegevens
Hoofdauteurs: Lo, Anthony W. I., Sprung, Carl N., Fouladi, Bijan, Pedram, Mehrdad, Sabatier, Laure, Ricoul, Michelle, Reynolds, Gloria E., Murnane, John P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC133890/
https://ncbi.nlm.nih.gov/pubmed/12052890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.13.4836-4850.2002
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