Chromosome Instability as a Result of Double-Strand Breaks near Telomeres in Mouse Embryonic Stem Cells

Telomeres are essential for protecting the ends of chromosomes and preventing chromosome fusion. Telomere loss has been proposed to play an important role in the chromosomal rearrangements associated with tumorigenesis. To determine the relationship between telomere loss and chromosome instability i...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Lo, Anthony W. I., Sprung, Carl N., Fouladi, Bijan, Pedram, Mehrdad, Sabatier, Laure, Ricoul, Michelle, Reynolds, Gloria E., Murnane, John P.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 2002
Assuntos:	DNA Dynamics and Chromosome Structure
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC133890/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12052890/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.22.13.4836-4850.2002
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