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Chromosome Instability in mouse Embryonic Stem Cells

Embryonic Stem Cells (ESCs) are expected to show a stable euploid karyotype, but in the last decade (sub)chromosomal aberrations have been systematically described in these cell lines when maintained in vitro. Culture conditions and long-term culture have been traditionally proposed as possible fact...

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Autori principali: Gaztelumendi, Nerea, Nogués, Carme
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060510/
https://ncbi.nlm.nih.gov/pubmed/24937170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep05324
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