PIF1 disruption or NBS1 hypomorphism does not affect chromosome healing or fusion resulting from double-strand breaks near telomeres in murine embryonic stem cells

Telomerase serves to maintain telomeric repeat sequences at the ends of chromosomes. However, telomerase can also add telomeric repeat sequences at DNA double-strand breaks (DSBs), a process called chromosome healing. Here, we employed a method of inducing DSBs near telomeres to query the role of tw...

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Detaylı Bibliyografya
Asıl Yazarlar: Reynolds, Gloria E., Gao, Qing, Miller, Douglas, Snow, Bryan E., Harrington, Lea A., Murnane, John. P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3208378/
https://ncbi.nlm.nih.gov/pubmed/21945094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.09.002
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