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Curcumin inhibits Akt/mTOR signaling through protein phosphatase-dependent mechanism

Akt/mTOR signaling plays an important role in tumorigenesis and is dysregulated in many tumors, especially metastatic prostate cancers. Curcumin has been shown to effectively prevent or inhibit prostate cancer in vivo and inhibit Akt/mTOR signaling in vitro, but the mechanism(s) remains unclear. Her...

詳細記述

保存先:
書誌詳細
主要な著者: Yu, Siwang, Shen, Guoxiang, Khor, Tin Oo, Kim, Jung-Hwan, Kong, Ah-Ng
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596943/
https://ncbi.nlm.nih.gov/pubmed/18790744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-2400
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