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Sulbactam Forms Only Minimal Amounts of Irreversible Acrylate-Enzyme With SHV-1 β-Lactamase
Sulbactam is a mechanism-based inhibitor of β-lactamase enzymes used in clinical practice. It undergoes a complex series of chemical reactions in the active site that have been studied extensively in the past three decades. However, the actual species that gives rise to inhibition in a clinical sett...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596720/ https://ncbi.nlm.nih.gov/pubmed/17630699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi7006146 |
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