Monoacylglycerol lipase regulates 2-arachidonoylglycerol action and arachidonic acid levels

The structure-activity relationships of organophosphorus (OP) and organosulfur compounds were examined in vitro and in vivo as inhibitors of mouse brain monoacylglycerol lipase (MAGL) hydrolysis of 2-arachidonoylglycerol (2-AG) and agonist binding at the CB1 receptor. Several compounds showed except...

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Detaylı Bibliyografya
Asıl Yazarlar: Nomura, Daniel K., Hudak, Carolyn S.S., Ward, Anna M., Burston, James J., Issa, Roger S., Fisher, Karl J., Abood, Mary E., Wiley, Jenny L., Lichtman, Aron H., Casida, John E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593629/
https://ncbi.nlm.nih.gov/pubmed/18752948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.08.007
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