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Inhibition of monoacylglycerol lipase and fatty acid amide hydrolase by analogues of 2-arachidonoylglycerol

1. The pharmacology of monoacylglycerol lipase (MAGL) is not well understood. In consequence, the abilities of a series of analogues of 2-arachidonoylglycerol (2-AG) to inhibit cytosolic 2-oleoylglycerol and membrane-bound anandamide hydolysis by MAGL and fatty acid amide hydrolase (FAAH), respectiv...

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Hlavní autoři: Ghafouri, Nazdar, Tiger, Gunnar, Razdan, Raj K, Mahadevan, Anu, Pertwee, Roger G, Martin, Billy R, Fowler, Christopher J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1575926/
https://ncbi.nlm.nih.gov/pubmed/15492019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0705948
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