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Ras Is Required for the Cyclic AMP-Dependent Activation of Rap1 via Epac2
Exchange proteins activated by cAMP (cyclic AMP) 2 (Epac2) is a guanine nucleotide exchange factor for Rap1, a small G protein involved in many cellular functions, including cell adhesion, differentiation, and exocytosis. Epac2 interacts with Ras-GTP via a Ras association (RA) domain. Previous studi...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology (ASM)
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2593374/ https://ncbi.nlm.nih.gov/pubmed/18824540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01060-08 |
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