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Cyclic AMP-Mediated Inhibition of Cell Growth Requires the Small G Protein Rap1
In many normal and transformed cell types, the intracellular second messenger cyclic AMP (cAMP) blocks the effects of growth factors and serum on mitogenesis, proliferation, and cell cycle progression. cAMP exerts these growth-inhibitory effects via inhibition of the mitogen-activated protein (MAP)...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2001
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC86997/ https://ncbi.nlm.nih.gov/pubmed/11340161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.11.3671-3683.2001 |
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