Ras Is Required for the Cyclic AMP-Dependent Activation of Rap1 via Epac2

Exchange proteins activated by cAMP (cyclic AMP) 2 (Epac2) is a guanine nucleotide exchange factor for Rap1, a small G protein involved in many cellular functions, including cell adhesion, differentiation, and exocytosis. Epac2 interacts with Ras-GTP via a Ras association (RA) domain. Previous studi...

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Bibliografiset tiedot
Päätekijät: Liu, Chang, Takahashi, Maho, Li, Yanping, Song, Shuang, Dillon, Tara J., Shinde, Ujwal, Stork, Philip J. S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2008
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2593374/
https://ncbi.nlm.nih.gov/pubmed/18824540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01060-08
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