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Protein Kinase A-independent Ras Protein Activation Cooperates with Rap1 Protein to Mediate Activation of the Extracellular Signal-regulated Kinases (ERK) by cAMP

Cyclic adenosine monophosphate (cAMP) is an important mediator of hormonal stimulation of cell growth and differentiation through its activation of the extracellular signal-regulated kinase (ERK) cascade. Two small G proteins, Ras and Rap1, have been proposed to mediate this activation, with either...

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Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Li, Yanping, Dillon, Tara J., Takahashi, Maho, Earley, Keith T., Stork, Philip J. S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076829/
https://ncbi.nlm.nih.gov/pubmed/27531745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.730978
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