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The Interaction of Epac1 and Ran Promotes Rap1 Activation at the Nuclear Envelope
Epac1 (exchange protein directly activated by cyclic AMP [cAMP]) couples intracellular cAMP to the activation of Rap1, a Ras family GTPase that regulates cell adhesion, proliferation, and differentiation. Using mass spectrometry, we identified the small G protein Ran and Ran binding protein 2 (RanBP...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916442/ https://ncbi.nlm.nih.gov/pubmed/20547757 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00242-10 |
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