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Pkd1 Inactivation Induced in Adulthood Produces Focal Cystic Disease
Autosomal dominant polycystic kidney disease, the most common monogenetic disorder, is characterized by gradual replacement of normal renal parenchyma by fluid-filled cysts. Mutations in either PKD1 or PKD2 cause autosomal dominant polycystic kidney disease. Pkd1(−/−) or Pkd2(−/−) mice develop rapid...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Nephrology
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2588099/ https://ncbi.nlm.nih.gov/pubmed/18776127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007101139 |
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