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Pkd1 Inactivation Induced in Adulthood Produces Focal Cystic Disease

Autosomal dominant polycystic kidney disease, the most common monogenetic disorder, is characterized by gradual replacement of normal renal parenchyma by fluid-filled cysts. Mutations in either PKD1 or PKD2 cause autosomal dominant polycystic kidney disease. Pkd1(−/−) or Pkd2(−/−) mice develop rapid...

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Detalhes bibliográficos
Main Authors: Takakura, Ayumi, Contrino, Leah, Beck, Alexander W., Zhou, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2588099/
https://ncbi.nlm.nih.gov/pubmed/18776127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2007101139
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