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CREB, ATF AND AP-1 TRANSCRIPTION FACTORS REGULATE IFN-γ SECRETION BY HUMAN T CELLS IN RESPONSE TO MYCOBACTERIAL ANTIGEN
IFN-γ production by T cells is pivotal for defense against many pathogens, and the proximal promoter of IFN-γ, −73 to −48 bp upstream of the transcription start site, is essential for its expression. However, transcriptional regulation mechanisms through this promoter in primary human cells remain u...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587306/ https://ncbi.nlm.nih.gov/pubmed/18641343 |
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