ESAT-6 Inhibits Production of IFN-γ by Mycobacterium tuberculosis-Responsive Human T Cells()

The Mycobacterium tuberculosis early secreted Ag of 6 kDa (ESAT-6) is a potent Ag for human T cells and is a putative vaccine candidate. However, ESAT-6 also contributes to virulence in animal models, mediates cellular cytolysis, and inhibits IL-12 production by mononuclear phagocytes. We evaluated...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Immunol
Main Authors: Wang, Xisheng, Barnes, Peter F., Dobos-Elder, Karen M., Townsend, James C., Chung, Yoon-tae, Shams, Homayoun, Weis, Stephen E., Samten, Buka
Formato: Artigo
Idioma:Inglês
Publicado: 2009
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5488288/
https://ncbi.nlm.nih.gov/pubmed/19265145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803579
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares