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Contribution of CD8(+) T Cells to Gamma Interferon Production in Human Tuberculosis

The proportions of peripheral blood mononuclear cells (PBMC), CD4(+) T cells, and CD8(+) T cells that produce gamma interferon (IFN-γ) in response to Mycobacterium tuberculosis were markedly reduced in tuberculosis patients, particularly in those with severe disease. Depletion of CD4(+) but not CD8(...

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Detalhes bibliográficos
Main Authors: Shams, Homayoun, Wizel, Benjamin, Weis, Stephen E., Samten, Buka, Barnes, Peter F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC98319/
https://ncbi.nlm.nih.gov/pubmed/11292783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.69.5.3497-3501.2001
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