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CD4(+) T Cells and the Proinflammatory Cytokines Gamma Interferon and Interleukin-6 Contribute to Alveolar Bone Loss in Mice

In this study, we used a mouse model to examine the role of the adaptive immune response in alveolar bone loss induced by oral infection with the human gram-negative anaerobic bacterium Porphyromonas gingivalis. Severe combined immunodeficient mice, which lack B and T lymphocytes, exhibited consider...

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Bibliografische gegevens
Hoofdauteurs: Baker, Pamela J., Dixon, Mark, Evans, R. Todd, Dufour, Lisa, Johnson, Ellis, Roopenian, Derry C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 1999
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC96585/
https://ncbi.nlm.nih.gov/pubmed/10338484
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