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CD4(+) T Cells and the Proinflammatory Cytokines Gamma Interferon and Interleukin-6 Contribute to Alveolar Bone Loss in Mice

In this study, we used a mouse model to examine the role of the adaptive immune response in alveolar bone loss induced by oral infection with the human gram-negative anaerobic bacterium Porphyromonas gingivalis. Severe combined immunodeficient mice, which lack B and T lymphocytes, exhibited consider...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Baker, Pamela J., Dixon, Mark, Evans, R. Todd, Dufour, Lisa, Johnson, Ellis, Roopenian, Derry C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96585/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10338484/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.6.2804-2809.1999
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