Llwytho...
β-arrestin mediated localization of Smoothened to the primary cilium
β-arrestins have important roles in the regulation of seven-transmembrane receptors (7TMRs). Smoothened (Smo) is a 7TMR that mediates effects of Hedgehog on developmental processes and whose dysregulation may cause tumorigenesis. β-arrestins are required for endocytosis of Smo and signaling to Gli t...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
2008
|
| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587210/ https://ncbi.nlm.nih.gov/pubmed/18497258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1157983 |
| Tagiau: |
Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
|