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Smoothened determines β-arrestin–mediated removal of the G protein–coupled receptor Gpr161 from the primary cilium

Dynamic changes in membrane protein composition of the primary cilium are central to development and homeostasis, but we know little about mechanisms regulating membrane protein flux. Stimulation of the sonic hedgehog (Shh) pathway in vertebrates results in accumulation and activation of the effecto...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Pal, Kasturi, Hwang, Sun-hee, Somatilaka, Bandarigoda, Badgandi, Hemant, Jackson, Peter K., DeFea, Kathryn, Mukhopadhyay, Saikat
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4810300/
https://ncbi.nlm.nih.gov/pubmed/27002170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201506132
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