The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner

The role of basal suppression of the sonic hedgehog (Shh) pathway and its interaction with Indian hedgehog (Ihh) signaling during limb/skeletal morphogenesis is not well understood. The orphan G protein-coupled receptor Gpr161 localizes to primary cilia and functions as a negative regulator of Shh s...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Development
Main Authors: Hwang, Sun-hee, White, Kevin A., Somatilaka, Bandarigoda N., Shelton, John M., Richardson, James A., Mukhopadhyay, Saikat
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825871/
https://ncbi.nlm.nih.gov/pubmed/29222391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.154054
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados