Derepression of sonic hedgehog signaling upon Gpr161 deletion unravels forebrain and ventricular abnormalities

Inverse gradients of transcriptional repressors antagonize the transcriptional effector response to morphogens. However, the role of such inverse regulation might not manifest solely from lack of repressors. Sonic hedgehog (Shh) patterns the forebrain by being expressed ventrally; however, absence o...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Dev Biol
Autores principales: Shimada, Issei S., Somatilaka, Bandarigoda N., Hwang, Sun-Hee, Anderson, Ashley G., Shelton, John M., Rajaram, Veena, Konopka, Genevieve, Mukhopadhyay, Saikat
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497453/
https://ncbi.nlm.nih.gov/pubmed/30914320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2019.03.011
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares