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K-Ras Nanoclustering is Subverted by Over-expression of the Scaffold Protein Galectin-3
The spatial organization of K-Ras proteins into nanoclusters on the plasma membrane is essential for high fidelity signal transduction. The mechanism underlying K-Ras nanoclustering is unknown. We show here that K-Ras.GTP recruits Galectin-3 (Gal-3) from the cytosol to the plasma membrane where it b...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2587079/ https://ncbi.nlm.nih.gov/pubmed/18701484 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1117 |
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