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Electrostatic Interactions Positively Regulate K-Ras Nanocluster Formation and Function

The organization of Ras proteins into plasma membrane nanoclusters is essential for high-fidelity signal transmission, but whether the nanoscale enviroments of different Ras nanoclusters regulate effector interactions is unknown. We show using high-resolution spatial mapping that Raf-1 is recruited...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Plowman, Sarah J., Ariotti, Nicholas, Goodall, Andrew, Parton, Robert G., Hancock, John F.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447143/
https://ncbi.nlm.nih.gov/pubmed/18458061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00050-08
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