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Electrostatic Interactions Positively Regulate K-Ras Nanocluster Formation and Function
The organization of Ras proteins into plasma membrane nanoclusters is essential for high-fidelity signal transmission, but whether the nanoscale enviroments of different Ras nanoclusters regulate effector interactions is unknown. We show using high-resolution spatial mapping that Raf-1 is recruited...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2447143/ https://ncbi.nlm.nih.gov/pubmed/18458061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00050-08 |
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