Mathematical Modeling of K-Ras Nanocluster Formation on the Plasma Membrane

K-Ras functions as a critical node in the mitogen-activated protein kinase (MAPK) pathway that regulates key cellular functions including proliferation, differentiation, and apoptosis. Following growth factor receptor activation K-Ras.GTP forms nanoclusters on the plasma membrane through interaction...

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Hlavní autoři: Tian, Tianhai, Plowman, Sarah J., Parton, Robert G., Kloog, Yoel, Hancock, John F.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2010
Témata:
Membrane
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905126/
https://ncbi.nlm.nih.gov/pubmed/20643072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.04.055
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