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Signal Integration by Lipid-Mediated Spatial Cross Talk between Ras Nanoclusters

Lipid-anchored Ras GTPases form transient, spatially segregated nanoclusters on the plasma membrane that are essential for high-fidelity signal transmission. The lipid composition of Ras nanoclusters, however, has not previously been investigated. High-resolution spatial mapping shows that different...

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Detalhes bibliográficos
Main Authors: Zhou, Yong, Liang, Hong, Rodkey, Travis, Ariotti, Nicholas, Parton, Robert G., Hancock, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023829/
https://ncbi.nlm.nih.gov/pubmed/24366544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01227-13
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