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Epidermal Growth Factor Receptor Activation Remodels the Plasma Membrane Lipid Environment To Induce Nanocluster Formation

Signal transduction is regulated by the lateral segregation of proteins into nanodomains on the plasma membrane. However, the molecular mechanisms that regulate the lateral segregation of cell surface receptors, such as receptor tyrosine kinases, upon ligand binding are unresolved. Here we used high...

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Detalhes bibliográficos
Main Authors: Ariotti, Nicholas, Liang, Hong, Xu, Yufei, Zhang, Yueqiang, Yonekubo, Yoshiya, Inder, Kerry, Du, Guangwei, Parton, Robert G., Hancock, John F., Plowman, Sarah J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2916403/
https://ncbi.nlm.nih.gov/pubmed/20516214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01615-09
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