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Caveolae regulate the nanoscale organization of the plasma membrane to remotely control Ras signaling

The molecular mechanisms whereby caveolae exert control over cellular signaling have to date remained elusive. We have therefore explored the role caveolae play in modulating Ras signaling. Lipidomic and gene array analyses revealed that caveolin-1 (CAV1) deficiency results in altered cellular lipid...

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Bibliografske podrobnosti
Main Authors: Ariotti, Nicholas, Fernández-Rojo, Manuel A., Zhou, Yong, Hill, Michelle M., Rodkey, Travis L., Inder, Kerry L., Tanner, Lukas B., Wenk, Markus R., Hancock, John F., Parton, Robert G.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2014
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3941050/
https://ncbi.nlm.nih.gov/pubmed/24567358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201307055
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