Nucleophosmin and Nucleolin Regulate K-Ras Plasma Membrane Interactions and MAPK Signal Transduction

The spatial organization of Ras proteins into nanoclusters on the inner leaflet of the plasma membrane is essential for high fidelity signaling through the MAPK pathway. Here we identify two selective regulators of K-Ras nanoclustering from a proteomic screen for K-Ras interacting proteins. Nucleoph...

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Detaylı Bibliyografya
Asıl Yazarlar: Inder, Kerry L., Lau, Chiyan, Loo, Dorothy, Chaudhary, Natasha, Goodall, Andrew, Martin, Sally, Jones, Alun, van der Hoeven, Dharini, Parton, Robert G., Hill, Michelle M., Hancock, John F.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2009
Konular:
Mechanisms of Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788890/
https://ncbi.nlm.nih.gov/pubmed/19661056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.001537
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