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H-Ras Nanocluster Stability Regulates the Magnitude of MAPK Signal Output
H-Ras is a binary switch that is activated by multiple co-factors and triggers several key cellular pathways one of which is MAPK. The specificity and magnitude of downstream activation is achieved by the spatio-temporal organization of the active H-Ras in the plasma membrane. Upon activation, the G...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Public Library of Science
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2916832/ https://ncbi.nlm.nih.gov/pubmed/20700538 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011991 |
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