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STIM1 gates TRPC channels but not Orai1 by electrostatic interaction
The receptor-evoked Ca(2+) signal includes activation of the store-operated channels (SOCs) TRPC and Orai channels. Although both are gated by STIM1, it is not known how STIM1 gates the channels and whether STIM1 gates the TRPCs and Orais by the same mechanism. Here, we report the molecular mechanis...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586614/ https://ncbi.nlm.nih.gov/pubmed/18995841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.09.020 |
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