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Polarized but differential localization and recruitment of STIM1/Orai1 and STIM1/TRPC channels in secretory cells
Polarized Ca(2+) signals in secretory epithelial cells are determined by compartmentalized localization of Ca(2+) signaling proteins at the apical pole. Recently the ER Ca(2+) sensor STIM1 and the Orai channels were shown to play a critical role in store-dependent Ca(2+) influx. STIM1 also gates the...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021582/ https://ncbi.nlm.nih.gov/pubmed/21054717 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2010.01138.x |
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