Polarized but differential localization and recruitment of STIM1/Orai1 and STIM1/TRPC channels in secretory cells

Polarized Ca(2+) signals in secretory epithelial cells are determined by compartmentalized localization of Ca(2+) signaling proteins at the apical pole. Recently the ER Ca(2+) sensor STIM1 and the Orai channels were shown to play a critical role in store-dependent Ca(2+) influx. STIM1 also gates the...

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Bibliographic Details
Main Authors: Hong, Jeong Hee, Li, Qin, Kim, Min Seuk, Shin, Dong Min, Feske, Stefan, Birnbaumer, Lutz, Cheng, Kwong Tai, Ambudkar, Indu S., Muallem, Shmuel
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021582/
https://ncbi.nlm.nih.gov/pubmed/21054717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2010.01138.x
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