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Structure-Based Approach to the Development of Potent and Selective Inhibitors of Dihydrofolate Reductase from Cryptosporidium

Cryptosporidiosis is an emerging infectious disease that can be life-threatening in an immune-compromised individual and causes gastrointestinal distress lasting up to 2 weeks in an immune-competent individual. There are few therapeutics available for effectively treating this disease. We have been...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Bolstad, David B., Bolstad, Erin S. D., Frey, Kathleen M., Wright, Dennis L., Anderson, Amy C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584871/
https://ncbi.nlm.nih.gov/pubmed/18834108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8009124
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