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Structure-Based Approach to the Development of Potent and Selective Inhibitors of Dihydrofolate Reductase from Cryptosporidium

Cryptosporidiosis is an emerging infectious disease that can be life-threatening in an immune-compromised individual and causes gastrointestinal distress lasting up to 2 weeks in an immune-competent individual. There are few therapeutics available for effectively treating this disease. We have been...

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Detaylı Bibliyografya
Asıl Yazarlar: Bolstad, David B., Bolstad, Erin S. D., Frey, Kathleen M., Wright, Dennis L., Anderson, Amy C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584871/
https://ncbi.nlm.nih.gov/pubmed/18834108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8009124
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