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Dual Roles of Glycosyl Torsion Angle Conformation and Stereochemical Configuration in Butadiene Oxide-Derived N1 β-Hydroxyalkyl Deoxyinosine Adducts: A Structural Perspective
The solution structure of the N1-(1-hydroxy-3-buten-2(R)-yl)-2′-deoxyinosine adduct arising from the alkylation of adenine N1 by butadiene epoxide (BDO), followed by deamination to deoxyinosine, was determined, in the oligodeoxynucleotide d(CGGACXAGAAG)•d(CTTCTCGTCCG). This oligodeoxynucleotide cont...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2005
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2584607/ https://ncbi.nlm.nih.gov/pubmed/16022502 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx050023x |
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