Structure of the 1,4-Bis(2'-deoxyadenosin-N(6)-yl)-2R,3R-butanediol Crosslink Arising from Alkylation of the Human N-ras Codon 61 by Butadiene Diepoxide

The solution structure of the 1,4-bis(2'-deoxyadenosin-N(6)-yl)-2R,3R-butanediol crosslink arising from N(6)-dA alkylation of nearest neighbor adenines by butadiene diepoxide (BDO(2)) was determined in the oligodeoxynucleotide 5' - d(CGGACXYGAAG)•d(CTTCTCGTCCG)-3'. This oligodeoxynucl...

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Hauptverfasser: Merritt, W. Keither, Nechev, Lubomir V., Scholdberg, Tandace A., Dean, Stephen M., Kiehna, Sarah E., Chang, Johanna C., Harris, Thomas M., Harris, Constance M., Lloyd, R. Stephen, Stone, Michael P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2005
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585418/
https://ncbi.nlm.nih.gov/pubmed/16042385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi047263g
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