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Structure of the 1,4-Bis(2′-deoxyadenosin-N(6)-yl)-2S,3S-butanediol Intra-strand DNA Cross-link Arising from Butadiene Diepoxide in the Human N-ras Codon 61 Sequence

The 1,4-bis(2′-deoxyadenosin-N(6)-yl)-2S,3S-butanediol intra-strand DNA cross-link arises from bis-alkylation of tandem N(6)-dA sites in DNA by R,R-butadiene diepoxide (BDO(2)). The oligodeoxynucleotide 5′-d(C(1)G(2)G(3)A(4)C(5)X(6)Y(7)G(8)A(9)A(10)G(11))-3′·5′-d(C(12)T(13)T(14)C(15)T(16)T(17)G(18)T...

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Bibliografski detalji
Glavni autori: Xu, Wen, Merritt, W. Keither, Nechev, Lubomir V., Harris, Thomas M., Harris, Constance M., Lloyd, R. Stephen, Stone, Michael P.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597494/
https://ncbi.nlm.nih.gov/pubmed/17256975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx060210a
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