Intracellular alkalization causes pain sensation through activation of TRPA1 in mice

Vertebrate cells require a very narrow pH range for survival. Cells accordingly possess sensory and defense mechanisms for situations where the pH deviates from the viable range. Although the monitoring of acidic pH by sensory neurons has been attributed to several ion channels, including transient...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Fujita, Fumitaka, Uchida, Kunitoshi, Moriyama, Tomoko, Shima, Asako, Shibasaki, Koji, Inada, Hitoshi, Sokabe, Takaaki, Tominaga, Makoto
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2008
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582441/
https://ncbi.nlm.nih.gov/pubmed/19033673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35957
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