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Intracellular alkalization causes pain sensation through activation of TRPA1 in mice

Vertebrate cells require a very narrow pH range for survival. Cells accordingly possess sensory and defense mechanisms for situations where the pH deviates from the viable range. Although the monitoring of acidic pH by sensory neurons has been attributed to several ion channels, including transient...

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Detaylı Bibliyografya
Asıl Yazarlar: Fujita, Fumitaka, Uchida, Kunitoshi, Moriyama, Tomoko, Shima, Asako, Shibasaki, Koji, Inada, Hitoshi, Sokabe, Takaaki, Tominaga, Makoto
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582441/
https://ncbi.nlm.nih.gov/pubmed/19033673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35957
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