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Inhibitory effects of monoterpenes on human TRPA1 and the structural basis of their activity

TRPA1, one of the transient receptor potential channels, has been reported to be involved in nociception and inflammatory pain, suggesting that this molecule could be a promising target for the development of analgesic agents. We screened several monoterpene analogs of camphor, which is known to inh...

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Autori principali: Takaishi, Masayuki, Uchida, Kunitoshi, Fujita, Fumitaka, Tominaga, Makoto
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Japan 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889502/
https://ncbi.nlm.nih.gov/pubmed/24122170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12576-013-0289-0
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