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Inhibitory effects of monoterpenes on human TRPA1 and the structural basis of their activity

TRPA1, one of the transient receptor potential channels, has been reported to be involved in nociception and inflammatory pain, suggesting that this molecule could be a promising target for the development of analgesic agents. We screened several monoterpene analogs of camphor, which is known to inh...

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Detalhes bibliográficos
Main Authors: Takaishi, Masayuki, Uchida, Kunitoshi, Fujita, Fumitaka, Tominaga, Makoto
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Japan 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889502/
https://ncbi.nlm.nih.gov/pubmed/24122170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12576-013-0289-0
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