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Inhibitory effects of monoterpenes on human TRPA1 and the structural basis of their activity

TRPA1, one of the transient receptor potential channels, has been reported to be involved in nociception and inflammatory pain, suggesting that this molecule could be a promising target for the development of analgesic agents. We screened several monoterpene analogs of camphor, which is known to inh...

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Bibliografiske detaljer
Main Authors: Takaishi, Masayuki, Uchida, Kunitoshi, Fujita, Fumitaka, Tominaga, Makoto
Format: Artigo
Sprog:Inglês
Udgivet: Springer Japan 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3889502/
https://ncbi.nlm.nih.gov/pubmed/24122170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12576-013-0289-0
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