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Hypotonicity-induced cell swelling activates TRPA1

Hypotonic solutions can cause painful sensations in nasal and ocular mucosa through molecular mechanisms that are not entirely understood. We clarified the ability of human TRPA1 (hTRPA1) to respond to physical stimulus, and evaluated the response of hTRPA1 to cell swelling under hypotonic condition...

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Bibliografiska uppgifter
I publikationen:J Physiol Sci
Huvudupphovsmän: Fujita, Fumitaka, Uchida, Kunitoshi, Takayama, Yasunori, Suzuki, Yoshiro, Takaishi, Masayuki, Tominaga, Makoto
Materialtyp: Artigo
Språk:Inglês
Publicerad: Springer Japan 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351518/
https://ncbi.nlm.nih.gov/pubmed/28623463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12576-017-0545-9
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