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Hypotonicity-induced cell swelling activates TRPA1

Hypotonic solutions can cause painful sensations in nasal and ocular mucosa through molecular mechanisms that are not entirely understood. We clarified the ability of human TRPA1 (hTRPA1) to respond to physical stimulus, and evaluated the response of hTRPA1 to cell swelling under hypotonic condition...

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Detalles Bibliográficos
Publicado en:J Physiol Sci
Main Authors: Fujita, Fumitaka, Uchida, Kunitoshi, Takayama, Yasunori, Suzuki, Yoshiro, Takaishi, Masayuki, Tominaga, Makoto
Formato: Artigo
Idioma:Inglês
Publicado: Springer Japan 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351518/
https://ncbi.nlm.nih.gov/pubmed/28623463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12576-017-0545-9
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