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Intracellular alkalization causes pain sensation through activation of TRPA1 in mice
Vertebrate cells require a very narrow pH range for survival. Cells accordingly possess sensory and defense mechanisms for situations where the pH deviates from the viable range. Although the monitoring of acidic pH by sensory neurons has been attributed to several ion channels, including transient...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Clinical Investigation
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2582441/ https://ncbi.nlm.nih.gov/pubmed/19033673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35957 |
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