Llwytho...
Regulated association of misfolded endoplasmic reticulum lumenal proteins with P58/DNAJc3
P58/DNAJc3 defends cells against endoplasmic reticulum (ER) stress. Most P58 molecules are translocated into the ER lumen, and here we report selective and stable binding to misfolded proteins by P58's TPR-containing N-terminal domain. In vitro, too, P58 binds selectively to a model misfolded p...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Nature Publishing Group
2008
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2580781/ https://ncbi.nlm.nih.gov/pubmed/18923430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.199 |
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