Endoplasmic Reticulum Degradation Requires Lumen to Cytosol Signaling: Transmembrane Control of Hrd1p by Hrd3p

Endoplasmic reticulum (ER)-associated degradation (ERAD) is required for ubiquitin-mediated destruction of numerous proteins. ERAD occurs by processes on both sides of the ER membrane, including lumenal substrate scanning and cytosolic destruction by the proteasome. The ER resident membrane proteins...

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Autori principali: Gardner, Richard G., Swarbrick, Gwendolyn M., Bays, Nathan W., Cronin, Stephen R., Wilhovsky, Sharon, Seelig, Linda, Kim, Christine, Hampton, Randolph Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2000
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189800/
https://ncbi.nlm.nih.gov/pubmed/11018054
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