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The Role of p58(IPK) in Protecting the Stressed Endoplasmic Reticulum

The preemptive quality control (pQC) pathway protects cells from acute endoplasmic reticulum (ER) stress by attenuating translocation of nascent proteins despite their targeting to translocons at the ER membrane. Here, we investigate the hypothesis that the DnaJ protein p58(IPK) plays an essential r...

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Detalhes bibliográficos
Main Authors: Rutkowski, D. Thomas, Kang, Sang-Wook, Goodman, Alan G., Garrison, Jennifer L., Taunton, Jack, Katze, Michael G., Kaufman, Randal J., Hegde, Ramanujan S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1951758/
https://ncbi.nlm.nih.gov/pubmed/17567950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-03-0272
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