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Mechanistic Investigations of the Pseudouridine Synthase RluA using RNA containing 5-Fluorouridine

The pseuoduridine synthases (Ψ synthases) isomerize uridine (U) to pseudouridine (Ψ) in RNA, and they fall into five families that share very limited sequence similarity but have the same overall fold and active site architecture, including an essential Asp. The mechanism by which the Ψ synthases op...

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Bibliografiske detaljer
Main Authors: Hamilton, Christopher S., Greco, Todd M., Vizthum, Caroline A., Ginter, Joy M., Johnston, Murray V., Mueller, Eugene G.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2580076/
https://ncbi.nlm.nih.gov/pubmed/17002302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061293x
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