The handling of the mechanistic probe 5-fluorouridine by the pseudouridine synthase TruA and its consistency with the handling of the same probe by the pseudouridine synthases TruB and RluA

RNA containing 5-fluorouridine (F(5)U) had previously been used to examine the mechanism of the pseudouridine synthase TruA, formerly known as pseudouridine synthase I [Gu et al. (1999) Proc. Natl. Acad. Sci. U.S.A. 96, 14270–14275]. From that work, it was reasonably concluded that the pseudouridine...

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Main Authors: McDonald, Marguerite K., Miracco, Edward J., Chen, Junjun, Xie, Yizhou, Mueller, Eugene G.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070203/
https://ncbi.nlm.nih.gov/pubmed/21142053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi101737z
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